Product Information产品信息

圣诺多肽冻干粉(美容肽)主要成分为乙酰基六肽-8,它是A cosmetic ingredient for wrinkle resistance that is popular all over the world. Acetyl hexapeptide-8 has been claimed to be used in many high-end cosmetics for wrinkle resistance. Its efficacy is comparable to that of botulinum toxin A, and it avoids the side effects of botulinum toxin itself, as well as the high cost of injection and use.

INCI Name乙酰基六肽-8(Acetyl Hexapeptide-8)Structural Formula
Nickname阿基瑞林(Argireline)或六胜肽或美容肽
Amino sequenceAc-Glu-Glu-Met-Glu-Arg-Arg-NH2
Molecular formulaC34H60N14O12S
molecular weight889.0
CAS616204-22-9
Product Characteristics产品特点

圣诺多肽冻干粉(美容肽)主要成分为乙酰基六肽-8,它Thanks to more comprehensive and balanced pharmacological advantages, acetyl hexapeptide-8 makes beauty wrinkle-resistant more simple and efficient.

Excellent wrinkle-resistant effect scientifically verified

Similar to Botulinum toxin, it can effectively reduce the depth of wrinkles caused by contraction of facial expression muscles.

Sterile without adding, high purity without invalidation

Sterile freeze-drying process, without any preservatives; purity close to 100%, long-term preservation is not inactivated.

Bioactive Peptides, Safe and Easy to Absorb

The bioactive polypeptide composed of amino acids has small molecular weight, easy absorption, safety and no toxic side effects.

Easier to use and more convenient to store

Freeze-dried powder of pure polypeptide is 1 gram per bottle; when used, it can be shaken by injecting 20 ml pure water.

Mechanism of action作用机理

圣诺多肽冻干粉(美容肽)主要成分为乙酰基六肽-8,Acetyl hexapeptide-8 is an oligopeptide that mimics the N-terminal of SNAP-25 and consists of six amino acids. Therefore, it can compete with SNAP-25 to interfere with the formation of SNARE protein complex, thereby inhibiting the excessive release of neurotransmitters (acetylcholine and catecholamine), partially blocking nerve transmission of muscle contraction information, relaxing facial muscles, and achieving the purpose of smoothing dynamic, static and fine lines. But it is different from the anesthesia mechanism of botulinum toxin A. It allows the muscles to move and express naturally, so it does not produce other side effects.

Product efficacy产品功效
scientific experiment

Effectively interfere with the formation of SNARE protein complexes, as shown in Figure 1.

Effectively inhibit the release of catecholamines to achieve a similar effect to BoNTs (botulinum toxin), see figure 2.

Human body testing

Ten female volunteers were treated with a cream containing 50 ppm acetyl hexapeptide-8 twice a day. The changes of wrinkle depth, skin silica gel model and laser scanning of silicone diaphragm lines after 15 and 30 days were measured. See figure 3.

Fourteen volunteers aged 39-63 were given 25 ppm acetylhexapeptide-8 cream around the eyes for 28 days twice a day. The average reduction of wrinkles was 16.26% and the highest was 31.8%. See figure 4.

Significantly reduce the depth of wrinkles on the skin surface, as shown in Fig. 5.

图一(注:摘自Liptec研究报告)

图二(注:摘自

图四

Cream containing 25 ppm acetyl hexapeptide-8 was used twice a day for 28 days. Contrast the wrinkles around the corners of the eyes before and after use.

图五

图三

Security安全性

Hypoallergenicity:

Acute toxicity test in mice was carried out. No toxic symptoms were observed for 20 days after intraperitoneal or intragastric administration of various doses.

Non-toxicity:

LANGT_DT_SAFE_CONB_C。

Usage & Dosage用法用量
01

The recommended usage of snake venom-like peptide in the product is 15-50 ppm.

02

In the final stage of cosmetic production, the process temperature should be controlled below 40 C.

03

When in use, the bottle is filled with about 20 ml of pure water, shaken and added to the product according to the prescription requirement.

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